The Curtiss Motorcycles building in New York 1909, was made famous by an unsolved murder of a young missionary woman, her body found stuffed in a steamer trunk (thanks Graham C!)

the Cycle and Automobile Trade Journal reported that the Tiger Cycle Works Co. "will handle the Royal and Reliance motorcycles during 1909." The space was soon home to The Aero Wheel Co., which supplied even more surprising merchandise, considering the location. 

 An advertisement in Aeronautics on August 1912 read, "Builds all kinds of wheels for Aeroplanes and Monoplanes. Standard or special sizes at very low prices."

The venerable building survived into the 21st century when it and the rest of the block--other than Ladder Company No. 4's station house--were demolished for the 51-story The Biltmore apartment building.

https://daytoninmanhattan.blogspot.com/2021/07/the-scene-of-infamous-murder-lost-782.html