The original Lupin the 3rd anime series (Part I) first aired in Japan on October 24, 1971, and ran until March 26, 1972. Like Tin Tin, it's loaded with cool vehicles

This is the actual opening credit sequence... how can this not be admired?! Mercedes-Benz SSK (W06, 1928-1932  thank you CoSC!)

and the 1st scene in the first episode, is a Gran Prix

according to the cartoon, it's a Ferrari 312 (312 = 3 liters, 12 cylinders)

The character Fujiko  that is either Lupin's girlfriend, or double agent spy, drives an Alpine in episode 1

and the bad guy in episode 2 drives a Messerschmitt